log  
logo
A Journal of Postdoctoral Research.
 
     Login   |   Register   
    ISSN : 2328-9791 Contact Us
left right
 
 
Cyanobacterial biofactories: combining evolved and synthetic genetic regulatory mechanism
     
 
Logan A. Brand, and George W. Owttrim, Ph.D.
University of Alberta
Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada T6G 2E9.
lbrand@ualberta.ca

While cyanobacteria hold the promise of producing useful bioproducts from little more than sunlight and carbon dioxide, their economic feasibility hinges on developing better mechanisms to manipulate gene expression in order to divert photosynthate towards product formation. A recent report demonstrates how combining simple feedback loops can improve the dynamic range of target gene expression while utilizing progressively lower concentrations of chemical inducers. As an extension of this work, we propose that utilizing regulatory elements that respond to changing temperatures could circumvent the need for exogenous chemical inducers, maintaining low background expression under non-induced conditions, and enhancing dynamic range via temperature induction of cyanobacterial cultures on an industrial scale.

 
btm
 
Discussion Board
 
Comments
 
     
btm
 
 
 
top
 
 
btm

 
submit_article Announcements
 
submit_article Submit Your Article
 
submit_article Post your Job
footer
 
 
home phone mail info@postdocjournal.com
 
twitter facebook social icon Social link You Tube sky
Click Here