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  Dr. EVELIN SZAKAL  
 
Address 1 :
Address 2 :
Title : Dr.
First Name : EVELIN
Last Name : SZAKAL
University/Institution : University of California San Francisco
Email ID : edszakal@gmail.com
City : SAN FRANCISCO
Country : United States
State : California
Zipcode : 94143
Company Name :
Area of Expertise
Infectious diseases of the GI tract, viral vaccines.
Brief Description of Research Interest :

Dr. Evelin D. Szakal, a native of Hungary, holds degrees in Microbiology(PhD), Biology (MSc), Economics (BS), and  English Languange and Literature (MSc). Since 2007, she has been a postdoctoral research scholar at the University of California, San Francisco (UCSF), where she is involved in the identification and characterization of protein complexes of Desulfovibrio vulgaris, a soil bacterium to be used in bioremediation by the DOE (Department of Energy). She earned her PhD at the University of Pécs Medical School, Institute for Microbiology and Immunology, where she focused on developing immunoassays identifying Shigella and EIEC, causing bacterial dysentery. Between 2000 and 2007, she was a full time researcher at the Vaccine Research Center at University of Tampere, Finland, where she investigated the presence of rotavirus and other gastroenteritis viruses like adenovirus and human caliciviruses (noro and sapoviruses) in pharmaceutical clinical trials of rotavirus vaccines in the pipeline of Wyeth, Merck and GSK. The latter two  (RotaTeq® and Rotarix®) were approved and recommended by the FDA and WHO in 2006 and 2008. Dr. Szakal has published more than 30 peer-reviewed works, including research papers, abstracts, presented at prestigious conferences in the fields of virology and bacteriology, some of her rotavirus vaccine related works received numerous attention (cited more than 150 times, including review papers, books and press release). She served as scientific writer at the ORWH conference in 2009 San Francisco, in the HIV working group, to write up a report which is a key aspect of the 10-year strategic planning initiative of the Office of Research on Women's Health/NIH. Besides her interest in science, she earned a degree in Economics at Szolnok College, Hungary, wrote her thesis in Marketing, on the role of marketing and sponsorship in the health-care industry. Since 2009 May she has been the Director of Marketing/PR of the executive council of the UCSF Postdoctoral Scholars Association.

Representative Publications :

ARTICLES


ZengSQ, Halkosalo A, Salminen M, Szakal ED, Karvonen A, and Vesikari T,  Norovirus Gastroenteritis in Young Children Receiving Human Rotavirus Vaccine. Scandinavian Journal of Infectious Diseases.2010 July.

ZengSQ, Halkosalo A, Salminen M, Szakal ED, Puustinen L, Vesikari T.One-step quantitative RT-PCR for the detection of rotavirus in acute gastroenteritis.J Virol Methods. 2008 Nov;153(2):238-40. Epub 2008 Sep.

VesikariT, Karvonen A, Puustinen L, Szakal ED, Zeng SQ, Delem A, De Vos B. Ashort report on highlights of world-wide development of RIX4414: An Europeanexperience. online Vaccine 2005 Aug Vaccine 24 2006.

VesikariT, Karvonen A, Puustinen L, Szakal ED, Zeng SQ, Delem A, De Vos B. 2004.Efficacy of RIX4414 live attenuated human rotavirus vaccine in Finnish infants.ThePediatric Infectious Disease Journal Volume 23, Number 10, October 2004. (cited:130)

Szakál D, Pál T. Comparison of media for the selective culture of enteroinvasive Escherichia coli. European Journal of Clinical Microbiology and Infectious Diseases 2003, 22: 235-241. (cited: 1)

Szakál D, Gadó I, Pál T. A colony blot immunoassay to detect enteroinvasive Escherichia coli and Shigella in water samples. Journal of Applied Microbiology 2001, 90 (2): 229-236

 

SUPPORT


Vesikari T et al and the Rotavirus Efficacy and Safety Trial (REST) Study Team. Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. N Engl J Med. 2006 Jan5;354(1):23-33.

Ruiz-Palacios GM et al and the Human Rotavirus Vaccine Study Group. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis.N Engl J Med. 2006 Jan5; 354(1):11-22.


PRESENTATIONS


Szakal ED, Halkosalo A, Salminen M, Zeng SQ, Karvonen A,Vesikari T. Human calicivirus in children with gastroenteritis in a rotavirusvaccine trial in Finland. Oral presentation. Third International CalicivirusConference  Nov 2007 - Cancun, Mexico

Szakal ED, Zeng SQ, S Räsänen, M Salminen, I Djatchkova, LPuustinen, A Haloksalo, A Karvonen, A Delem, A Poliszczack, JP Cassart, B DeVos, T Vesikari. Rotavirus RNAemia in rotavirus vaccine recipients andin infants with wild type rotavirus infection. Oral presentation. 2nd EuropeanRotavirus Biology Meeting, June 2007 - Stockholm, Sweden

Szakal ED, Zeng SQ, S Räsänen, M Salminen, I Djatchkova, LPuustinen, A Haloksalo, A Karvonen, A Delem, A Poliszczack, JP Cassart, B DeVos, T Vesikari. Rotavirus RNAemia in rotavirus vaccine recipients andi n infants with wild type rotavirus infection. Oral presentation. Rotavirus Antigenaemia, RNAemia and Viraemia Round Table Meeting, April 2007- Lisbon, Portugal

HLiu; M Dong; LL Yang; ED Szakal; S Allen; SC Hall; SJ Fisher; TC Hazen; JTGeller; ME Singer; J Jin; MD Biggin; HE Witkowska. Development and Refinementof an iTRAQ-Based “Tagless” Strategy for High-Throughput Purification and Identification of Soluble Protein Complexes; American Society for MassSpectrometry Annual Meeting 2010. Poster 135. Session: Proteomics: NewApproaches II.

Ming D et al. Protein Complex Analysis Project (PCAP): Protein Complex Purification and Identification by ”Tagless” Strategy. Poster. Abstract p.157. February 2009, Bethesda, MD. Genomics: GTL Contractor-Grantee Workshop VII, USDA-DOE Plant Feedstock Genomics for Bioenergy Awardee Workshop 2009.

Allen S et al. Protein Complex Analysis Project (PCAP): Multi-ProteinComplex Purification and Identification by Mass Spectrometry. Poster 119 North Bethesda, MD. Genomics: GTL Contractor-Grantee Workshop VI. and Metabolic Engineering Working Group Interagency Conference on Metabolic Engineering 2008

 

CITATIONS


"Rotavirus RNAemia in rotavirus vaccine recipients and in infants with wild type rotavirus infection" was cited

in Rotavirus Biology Meeting Report, and in the manufacturer's Press Release.


"Efficacy of RIX4414 live attenuated human rotavirusvaccine in Finnish infants" was cited in the Medical News Today article

GSK's Global Launch with Rotarix(TM) starts in Mexico(for rotavirus), and in the book Vaccines for Biodefence and Emerging and Neglected Diseases.

 
     
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