|
|
|
Dr. BHARAT JAGANNATHAN
|
|
|
|
|
|
Address 1
|
:
|
|
Address 2
|
:
|
|
Title
|
:
|
Dr.
|
First Name
|
:
|
BHARAT
|
Last Name
|
:
|
JAGANNATHAN
|
University/Institution
|
:
|
University of California
|
Email ID
|
:
|
bharatj@berkeley.edu
|
City
|
:
|
Berkeley
|
Country
|
:
|
United States
|
State
|
:
|
California
|
Zipcode
|
:
|
94720
|
|
|
|
|
Department
|
:
|
California Institute for Quantitative Biosciences
|
Company Name
|
:
|
|
Area of Research
|
protein folding
|
Area of Expertise
|
protein biochemistry/biophysics
|
Brief Description of Research Interest :
|
-
Identified important structural features of protein-‐protein and protein-‐cofactor interactions crucialfor photosynthetic activity
-
Devised innovative strategies for comprehensively characterizing the mechanisms by whichproteins fold into their proper three-‐dimensional structure
-
Developed a cutting-‐edge technique using antibody-‐antigen interactions to manipulate singleprotein molecules
-
Developed a method to simultaneously monitor multiple spectroscopic probes in proteins, whichwould report on long-‐range allosteric effects
-
Elucidated the assembly pathways of large multi-‐subunit protein complexes by identifying keyamino acids involved in binding
-
Discovered unique biological cofactors in membrane protein complexes that had eluded detectionfor twenty-‐five years
-
Devised a novel method for quantifying toxic free radicals in biological systems by spin trapping
|
Representative Publications :
|
-
Jagannathan, B. and Marqusee, S. (2013) Protein Folding and Unfolding Under Mechanical Force, Biopolymers, in press
-
Jagannathan, B., Elms, P., Bustamante, C. and Marqusee, S. (2012) Direct Observation of a Force- Induced Switch in the Mechanical Unfolding Pathway of a Protein, Proc. Nat. Acad. Sci. 109,17820-17825
-
Jagannathan, B., Dekat, S., Golbeck, J.H. and Lakshmi, K.V. (2010) A Site Directed Spin Labeling Study of the Assembly of the PsaC Subunit in Photosystem I, Biochemistry 49, 2398-‐2408
-
Jagannathan, B. and Golbeck, J.H. (2009) Understanding of the Binding Interface Between PsaC and the PsaA/PsaB Heterodimer in Photosystem I, Biochemistry 48, 5405-‐5416
-
Jagannathan, B. and Golbeck, J.H. (2009) Breaking Biological Symmetry in Membrane Proteins: The Asymmetric Orientation of PsaC on the Photosystem I Core, Cell. Mol. Life Sci. 66, 1257-‐1270
-
Jagannathan, B. and Golbeck, J.H. (2008) Unifying Principles in Homodimeric Type I Photosynthetic Reaction Centers: Properties of PscB and the FX, FA and FB Iron-‐Sulfur Clusters in Green Sulfur Bacteria, Biochim. Biophys. Acta 1777, 1535-‐1544
|
Resume
|
:
|
Download
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|