log  
logo
A Journal of Postdoctoral Research.
 
     Login   |   Register   
    ISSN : 2328-9791
left right
 
 
Hall of Fame
EDITORIAL BOARD
btm
 
top
  Dr. LAURA ADAMSON SMALL  
 
Address 1 :
Address 2 :
Title : Dr.
First Name : LAURA
Last Name : ADAMSON SMALL
University/Institution : University of Florida
Phone # : 352-294-4959
Email ID : ladamson@ufl.edu
City : Gainesville
Country : United States
State : Florida
Zipcode : 32601
Department : Pediatrics
Company Name :
Area of Research
Immunology and Microbiology
Area of Expertise
Virology
Brief Description of Research Interest :
My dissertation research focused on the role of Parvovirus B19 in cancers, particularly thyroid cancer. While B19 is ubiquitous and data does not suggest it is a causative agent of the cancers examined, its association with inflammatory pathways, specifically with upregulation of IL-6, such a possible bystander role for the virus in infected cells.

Currently, I am working on developing adeno-associated viral vectors for the targeting and treatment of thyroid cancers. Thyroid cancers develop from two main cell types: thyroid epithelial cells and c-cells. I am working on optimizing specific viral serotypes and promoters to target cancers derived from these cell types. The end goal is to deliver either apoptotic genes or gene capable of re-differentiating aggressive tumors to improve treatment of these cancers.
Representative Publications :
Adamson LA, Fowler LJ, Ewald AS, Clare-Salzler MJ, Hobbs JA.2013. Parvovirus B19 infection, persistence, and expression in a wide range ofadult and pediatric thyroid tumors and disease. Journal of Medical Virology. [Epub ahead of print] PMID#: 24265024
 
Polcz ME, Adamson LA, Lu X, Chang MH, FowlerLJ, Hobbs JA. 2013. Increased IL-6 detection in adult and pediatric lymphoidtissue harboring Parvovirus B19. Journalof Clinical Virology. 57(3):233-8. PMID#: 23522566
 
Polcz ME, Adamson LA, Datar RS, Fowler LJ, andHobbs JA. 2011. Detection of parvovirus B19 capsid proteins in testiculartissues. Urology, 79(3):744.e9-15. PMID#:22137539

 
Adamson LA, Fowler LJ, Clare-SalzlerMJ, Hobbs JA. 2010. ParvovirusB19 Infection in Hashimoto’s Thyroiditis, Papillary Thyroid Carcinoma, andAnaplastic Thyroid Carcinoma. Thyroid. 21(4): 411-417. PMID#: 21190433
 
Harper MM, Adamson L, Blits B, Bunge MB,Grozdanic SD, Sakaguchi DS. 2009. Brain-derived neurotrophic factor releasedfrom engineered mesenchymal stem cells attenuates glutamate- and hydrogenperoxide-mediated death of staurosporine differentiated RGC-5 cells.Experimental Eye Research. 89(4): 538-548. PMID#: 19524566
Resume : Download
 
     
btm
 
 
top
 
 
 
 
 
btm

 
footer
 
 
home phone mail info@postdocjournal.com
 
twitter facebook social icon Social link You Tube sky
Click Here