|
|
|
Dr. NICOLAS SZABO FRESNAIS
|
|
|
|
|
|
Address 1
|
:
|
|
Address 2
|
:
|
|
Title
|
:
|
Dr.
|
First Name
|
:
|
NICOLAS
|
Last Name
|
:
|
SZABO FRESNAIS
|
University/Institution
|
:
|
University of Utah
|
Email ID
|
:
|
nicolas.szabo@hsc.utah.edu
|
City
|
:
|
Salt Lake City
|
Country
|
:
|
United States
|
State
|
:
|
Utah
|
Zipcode
|
:
|
84103
|
|
|
|
|
Department
|
:
|
biochemistry
|
Company Name
|
:
|
|
Area of Research
|
Cell signaling, biochemistry.
|
Area of Expertise
|
cardiology
|
Brief Description of Research Interest :
|
I worked on the Interleukin 6 (IL-6) gene regulation in thyroid cells and on the effect of IL-6 in cardiac cells during my PhD. As a postdoc in biochemistry, my research has focused on protein-protein interactions regulated by phosphorylation. I am currently involved in a research project that focuses on D-peptide inhibitors for viral entries.
|
Representative Publications :
|
1. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19778-83. doi:
10.1073/pnas.1305427110. Epub 2013 Nov 18.
Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms.
Vandeput F, Szabo-Fresnais N, Ahmad F, Kho C, Lee A, Krall J, Dunlop A, Hazel
MW, Wohlschlegel JA, Hajjar RJ, Houslay MD, Manganiello VC, Movsesian MA.
2. Cell Signal. 2010 Jul;22(7):1143-52. doi: 10.1016/j.cellsig.2010.03.009. Epub
2010 Mar 11.
A new regulation of IL-6 production in adult cardiomyocytes by beta-adrenergic
and IL-1 beta receptors and induction of cellular hypertrophy by IL-6
trans-signalling.
Szabo-Fresnais N, Lefebvre F, Germain A, Fischmeister R, Pomérance M.
3. Mol Cell Endocrinol. 2008 Mar 12;284(1-2):28-37. doi: 10.1016/j.mce.2007.12.017.
Epub 2008 Jan 8.
Activation of the cAMP pathway synergistically increases IL-1-induced IL-6 gene
expression in FRTL-5 thyroid cells: involvement of AP-1 transcription factors.
Szabo-Fresnais N, Blondeau JP, Pomérance M.
|
Resume
|
:
|
Download
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|