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Address 2 :
Title : Dr.
First Name : MELANIE
Last Name : LOEDIGE
University/Institution : Formerly UPenn, Perelman School of Medicine
Email ID : mlnloedige@gmail.com
City : Currently
Country : Germany
State : Berlin
Zipcode : 10439
Company Name :
Area of Research
Drug Discovery and Development
Area of Expertise
Medicinal Chemistry
Brief Description of Research Interest :
therapeutics against infectious diseases, immune therapeutics, peptide synthesis, nucleotide synthesis, small molecule synthesis, natural product chemistry.
Representative Publications :
M. Lödige, L. Hiersch; Design and Synthesis of Novel Hybrid Molecules against Malaria; Int. J. Med. Chem. 2015, Article ID 458319.

M. Lödige; Design and Synthesis of Novel Antileishmanial Compounds; Int. J. Med. Chem. 2015, Article ID 302723.

M. Lödige; Design and Synthesis of Small Molecule Inhibitors against Protective Antigen of Bacillus anthracis; Journal of Postdoctoral Research 2014, 2, 1–16. doi.org/xgs

M. Lödige, M. D. Lewis, E. S. Paulsen, H. L. Esch, G. Pradel, L. Lehmann, R. Brun, G. Bringmann, A.-K. Mueller; A primaquine–chloroquine hybrid with dual activity against Plasmodium liver and blood stages; Int. J. Med. Microbiol. 2013, 303, 539–547. [Epub ahead of print, Aug 5 2013]

S. M. Husain, T. Stillger, P. Dünkelmann, M. Lödige, L. Walter, E. Breitling, M. Pohl, M. Bürchner, I. Krossing, M. Müller, D. Romano, F. Molinari; Stereoselective Reduction of 2-Hydroxy Ke-tones towards syn- and anti-1,2-Diols; Adv. Synth. Catal. 2011, 353, 2359–2362.

G. Bringmann, M. Lödige, A. K. Müller, M. Lewis, G. Pradel, H. Moll, U. Schurigt, L. Lehmann, R. Brun; Hybridverbindungen aus 4- und 8-Aminochinolinen zur prophylaktischen und therapeutischen Behandlung von Malaria und anderen parasitären Erkrankungen. Application No. WO2012048894 (A1), publication date 19.04.2012.

G. Bringmann, M. Lödige, R. Benz, A. Kronhardt, C. Beitzinger, H. Barth; Aminoquinolinium compounds: Inhibitors against the binary toxins of Bacillus anthracis. Application No. WO2011EP04846 20110928, publication date 05.04.2012.

M. Lödige; Synthesis and evaluation of novel drug classes against infectious diseases; Doctoral thesis, University of Würzburg 2013.

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