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A Journal of Postdoctoral Research.
 
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    ISSN : 2328-9791
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  Dr. SURESH SHARMA  
 
Address 1 :
Address 2 :
Title : Dr.
First Name : SURESH
Last Name : SHARMA
University/Institution : Penn State University
Email ID : sds20psu@gmail.com
City : University Park
Country : United States
State : Pennsylvania
Zipcode : 16802
Department : Biochemistry and Molecular Biology
Company Name :
Area of Research
Virology/mitochondrial toxicology
Brief Description of Research Interest :

Suresh wants to help make the world where there are effective therapies and vaccines to treat all diseases. In his own research in the Eberly college of Science at Penn State, he applies a variety of approaches to answer fundamental questions about virus biology that contribute to antiviral and vaccine development. 

Representative Publications :

Sharma,S.D. (2013) Hepatitis C virus 1b viral factors (Core, NS3 and NS5A) and increased risk of hepatocellular carcinoma. Hepatology (DOI: 10.1002/hep.26362). (Invited Editorial).

Arnold, J.J., Sharma, S.D., Smidansky, E.D., Feng, J.Y.,Ray, A.S., Cho, A., Perry, J., Vela, J.E., Xu, Y., Tian, Y., Kireeva, M.L.,Peterson, B.R., Kashlev, M., Zhong, W. and Cameron, C.E.(2012) HumanMitochondrial RNA Polymerase as an Off Target for Antiviral Ribonucleosides.PLOS Pathogens. 8(11): e1003030.

*William, D., *Bowzard, B., *Sharma, S.D., Wiens, M., Priya,R., Fujita, T., Cameron, C.E., Suryaprakash, S. (2012) The 3' UntranslatedRegions of Influenza Genomic Sequences are 5'PPP-Independent Ligands for RIG-I.PLos One. 7(3): e32661.  (* equal authorcontribution)

Sharma, S.D. (2010)Hepatitis C Virus: Molecular Biology and Current Therapeutic options. I.J. Med.Res. 131, 14-31. 

Sharma, S.D., Raghuraman, G., Lee, M.S., Prabhakar, N.R., andKumar, G.K. (2009) Intermittent hypoxia activates peptidylglycine{alpha}-amidating monooxygenase in rat brainstem via reactive oxygenspecies-mediated proteolytic processing. J Appl. Physiol. 106, 12-9.

Peng Y.J., Yuan G., Ramakrishnan D., Sharma S.D.,Bosch-Marce M., Kumar G.K., Semenza G.L., Prabhakar N.R. (2006) HeterozygousHIF-1{alpha} deficiency impairs carotid body-mediated systemic responses andreactive oxygen species generation in mice exposed to intermittent hypoxia. JPhysiol. 577, 705-16.

Kumar, G.K., Rai, V., Sharma, S.D., Ramakrishnan, D.P.,Peng, Y.-J., Souvannakitti, D., and Prabhakar, N.R. (2006) Chronic intermittenthypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenalmedulla via oxidative stress. J Physiol. 575, 229-39.

Huang, L., Jungwook, H., Sharma, S.D., Hargittai, M.R.S.,Yingfeng, C., Arnold, J.J., Kevin, R.D., and Cameron, CE. (2005) Hepatitis CVirus Nonstructural Protein 5A (NS5A) Is an RNA-binding Protein. J BiolChem.  280, 36417-28.

Sharma, S.D., Pandey, B.N., Mishra, K.P., and Sivakami, S.(2002) Amadori Product and AGE formation during Non-enzymatic Glycosylation ofBovine Serum Albumin in vitro.  J Biochem.Mol. Bio. Biophys. 6, 233-42.

Sharma, S.D., and Sivakami, S. (1998) Responses ofintestinal and renal alpha-glycosidases to alloxan and sreptozotocin-induceddiabetes: a comparative study. Biochem. Mol. Biol. Int. 44, 647-56.

 
     
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