A Journal of Postdoctoral Research.
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    ISSN : 2328-9791
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Let There Be Light Activated Drug Release
Stephan C. Jahn
University of Florida
Department of Medicinal Chemistry and UF Health Cancer Center, UFL, Gainesville, FL 32610, USA
In some instances systemic drug delivery, either orally or intravenously, may not be the ideal dosing strategy. Repeated intravenous injections are unpleasant and sometimes a more localized delivery is needed such as in treatment of a tumor. A method that would allow a reservoir of drug to be implanted in a patient and be released in a controlled manner on demand would allow repeated dosing in a localized area and could prove extremely beneficial in the clinic by limiting the total dose needed and therefore the related side effects. The present article highlights a new approach utilizing reservoir capped by a light-responsive membrane that can be made permeable using an external near-infrared light source that was recently published by Timko et al.

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