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Dr. DESHOU CAO
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Address 1
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Address 2
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Title
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Dr.
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First Name
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DESHOU
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Last Name
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CAO
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University/Institution
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University of California San Diego
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Email ID
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dcao@ucsd.edu
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City
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La Jolla
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Country
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United States
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State
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California
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Zipcode
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92093
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Department
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Division of Biological Sciences
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Company Name
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Area of Research
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Endocrinology/Diabetes, Neurobiology
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Area of Expertise
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Electrophysiology, Ion channels and nociception, Neural circuits, Olfaction, 2-photon imaging
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Brief Description of Research Interest :
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In my graduate work, I studied the role of TRP channels in nociception and the involvement of TRPV1 channels in diabetic peripheral neuropathy through ROS-p38MAPK signaling pathway. I also investigated the expression and function of TRPA1 channels in pancreatic beta cells. Currently,I work on how olfaction can drive attraction in the high brain center of drosophila and what neural circuits and neuromodulators are involved in this behavior.
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Representative Publications :
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Cao DS, Zhong L, Hsieh TH, Abooj M, Bishnoi M, HughesL, Premkumar LS. Expression of transientreceptor potential ankyrin 1 (TRPA1) and its role in insulin release from ratpancreatic beta cells. PLoS One. 2012;7(5):e38005.
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RaisinghaniM, Zhong L, Jeffry JA, Bishnoi M, Pabbidi RM, Pimentel F, Cao DS, Evans MS,Premkumar LS. Activation characteristics of transient receptor potentialankyrin 1 and its role in nociception. Am J Physiol Cell Physiol. 2011;301(3):C587-600.
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WaliaV, Yu Y, Cao D, Sun M, McLean JR, Hollier BG, Cheng J, Mani SA, Rao K,Premkumar L, Elble RC. Loss of breast epithelial marker hCLCA2 promotesepithelial-to-mesenchymal transition and indicates higher risk of metastasis.Oncogene. 2012;31(17):2237-46.
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Cao DS, Yu SQ, Premkumar LS. Modulation oftransient receptor potential vanilloid 4-mediated membrane currents andsynaptic transmission by protein kinase C. Mol Pain. 2009, 5:5.
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PabbidiRM, CaoDS, Parihar A, Pauza ME, Premkumar LS. Direct role of streptozotocin ininducing thermal hyperalgesia by enhanced expression of transient receptorpotential vanilloid 1 in sensory neurons. Mol Pharmacol. 2008, 73:995-1004.(Pabbidi RM and Cao DS contributed equally to this study)
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LinHW, Liu CZ, Cao D, Chen PY, Chen MF, Lin SZ, Mozayan M, Chen AF, PremkumarLS, Torry DS, Lee TJ. Endogenous methyl palmitate modulates nicotinicreceptor-mediated transmission in the superior cervical ganglion. Proc NatlAcad Sci U S A. 2008, 105:19526-31.
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Resume
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