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  Dr. MARCO DEMARIA  
 
Address 1 :
Address 2 :
Title : Dr.
First Name : MARCO
Last Name : DEMARIA
University/Institution : Buck Institute
Email ID : mdemaria@buckinstitute.org
City : Novato
Country : United States
State : California
Zipcode : 94945
Company Name :
Area of Research
Aging/Cancer
Area of Expertise
Molecular Biology
Brief Description of Research Interest :
I'm interested to unravel the molecular basis of cellular senescence, with a particular focus on the senescence-associated secretory phenotype (or SASP). The SASP includes several growth factors, proteases and cytokines that positively and negatively alter the microenvironment. I'm studying the contradictory roles of the SASP in cancer and wound healing. 
Representative Publications :


 

Chinta SJ, Lieu CA, Demaria M, Laberge RM, CampisiJ, Andersen JK, “Environmental stress,ageing and glial cell senescence: a novel mechanistic link to Parkinson'sdisease?”, J Intern Med. 2013;273(5):429-36.

 

Velarde MC, Demaria M, Campisi J, “Senescentcells and their secretory phenotype as targets for cancer therapy”, Interdiscip Top Gerontol. 2013;38:17-27.

 

Demaria M, CampisiJ, “Matters of life and breath: Arole for hypoxia in determining cell state”, Aging(Albany NY), 2012 Apr;3(4): 359-60.

 

Demaria M, Poli V, “PKM2, STAT3 and HIF-1α: The Warburg’s vicious circle”, JAK-STAT, 2012, 3: 1. In press.

Demaria M, Poli V, “Pro-malignant properties of STAT3 during chronic inflammation”,Oncotarget, 2012; 3(4):359-60.

Demaria M, Misale S, Giorgi C, Miano V,Camporeale A, Campisi J, Pinton P, Poli V, “Stat3can serve as a hit in the process of malignant transformation of primary cells”,Cell Death & Differentiation. 2012 Aug;19(8):1390-7.

Freund A, Laberge RM, Demaria M, Campisi J, “Lamin B1loss is a senescence-associated biomarker”, Mol Biol Cell, 2012 Jun;23(11):2066-75.

Haines B, Demaria M, Mao X, Xie L, Campisi J, Jin K, Greenberg DA, “Hypoxia-inducible factor-1 and neuroglobinexpression”, Neuroscience Letter.2012 Feb 10; 514(2):137-40.

DemariaM, Poli V, “From the nucleus to the mitochondria andback: the odyssey of a multitask STAT3”, Cell Cycle, 2011 Oct 1;10(19):3221-3222.

Demaria M, Giorgi C, Lebiedzinska M, Esposito G, D'Angeli L,Bartoli A, Gough DJ, Turkson J, Levy DE, Watson CJ, Wieckowski MR, Provero P,Pinton P, Poli V,

”ASTAT3-mediated metabolic switch is involved in tumour transformation and STAT3addiction”, Aging(Albany NY),2010 Nov 15; 2(11):823-842.


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