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  Dr. DEBASHIS MANDAL  
 
Address 1 :
Address 2 :
Title : Dr.
First Name : DEBASHIS
Last Name : MANDAL
University/Institution : Harvard University
Phone # : (858)361-7985
Email ID : debashismandal@fas.harvard.edu
City : Cambridge
Country : United States
State : Massachusetts
Zipcode : 02138
Department : Chemistry and Chemical Biology
Company Name :
Area of Research
Organic Chemistry, Medicinal Chemistry, Peptide Chemistry, Catalysis, Total Synthesis, Development of New Methodology, Drug Discovery
Area of Expertise
Organic Chemistry, Medicinal Chemistry, Peptide Chemistry, Catalysis, Total Synthesis, Development of New Methodology, Drug Discover
Brief Description of Research Interest :

Creative, experienced andhighly motivated synthetic organic chemist with depth knowledge in the area of totalsynthesis, C–H coupling, catalysis, fluorination, peptide chemistry, developmentof new synthetic methodologies, medicinal chemistry and drug discovery. Proven applicationof knowledge and problem-solving skills in the strategic planning and successfulexecution of multistep synthesis of biologically active natural products, smallmolecules, and highly cytotoxic anticancer agents. Having good organizationalskills, excellent written and communication skills, and experience of workingin highly interdisciplinary collaborative environments. 

Representative Publications :

–“Desacetoxy Tubulysin H andAnalogs Therof” (Patent)

Nicolaou, K.C.; Mandal, D.; Klahn, P.;Yin, J.; Vourloumis, D. (US Patent Serial No: 62/120,613)


–“Efficient Synthesis andBiological Study of Tetrapeptide Tubulysin and Analogs Thereof”

Nicolaou, K.C.; Mandal, D.; Klahn, P.;Yin, J.; Vourloumis, D. (Manuscript in Preparation for Publication)


–“Novel Derivatives ofUncialamycin and Methods of Synthesis”. (Submitted)

Nicolaou, K.C.; Lu, M.; MandalD.; Yu. R.


–“Novel Derivatives ofUncialamycin and Methods of Synthesis”. (Patent)

Nicolaou, K.C.; Lu, M.; Mandal,D.; Gangwar, S.; Chowdari, N.; Poudel, Y. (Patent No: PCT/US2014/051127)


–“Synthesisof Dragmacidin D via Direct C–H Couplings”. Mandal, D.; Yamaguchi, A.D.; Yamaguchi, J.; Itami, K. J. Am. Chem.Soc. 2011, 133, 19660–19663. Among Most Read Articles (November2011), Highlighted in Chemistry World.


–“OxidativeC–H/C–H Coupling of Azine and Indole/Pyrrole Nuclei: Palladium Catalysis andSynthesis of Eudistomin U”. Yamaguchi, A. D.; Mandal, D.; Yamaguchi, D.;Itami, K. Chem. Lett. 2011, 40, 555–557. Selected as Editor’s Choice. AmongMostAccessed Articles. Highlighted in Angew. Chem. Int. Ed. and Synlett.


–“Method for PreparingNitrogen-Containing Heterocyclic Compounds”. (Patent)

Itami, K.; Yamaguchi, J.; Mandal,D.; Yamaguchi, A. (Japan P2011–178752A)

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